March 1935

Studies on Blood Sugar and Glycosuria in Exophthalmic Goitre.

Author Affiliations

By William Thume Andersen. Pp. 206, with 16 illustrations. Copenhagen: Levin & Munksgaard, 1933.

Arch Intern Med (Chic). 1935;55(3):530-531. doi:10.1001/archinte.1935.00160210183015

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This book contains the author's thesis for the doctorate of medicine at the University of Copenhagen. The material comprised thirty-one patients with exophthalmic goiter and two with diabetes mellitus. In one case of diabetes, exophthalmic goiter was associated; in the other, myxedema. The patients with exophthalmic goiter were examined systematically for spontaneous glycosuria and for the response of the blood sugar to injections of dextrose. By these means some abnormality was demonstrated in nearly all. Andersen concludes that in uncomplicated exophthalmic goiter the blood sugar during fasting is normal in most instances most of the time, but that an occasional higher than normal value during fasting is found in more than one half of the cases, and that the alimentary blood sugar curve is increased in height and duration in most cases. Thyroidectomy is followed by a diminution in the abnormality of the alimentary blood sugar curve.

The renal threshold

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