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Article
July 1937

MONOCYTIC LEUKEMIACUTANEOUS MANIFESTATIONS OF THE NAEGELI AND SCHILLING TYPES; HEMOCYTOLOGIC DIFFERENTIATION

Author Affiliations

ROCHESTER, MINN.

From the Section on Dermatology and Syphilology and the Division of Medicine, the Mayo Clinic.

Arch Intern Med (Chic). 1937;60(1):51-63. doi:10.1001/archinte.1937.00180010054004
Abstract

It is important to distinguish between the so-called Naegeli type of monocytic leukemia (which many regard as a variant of myelogenous leukemia, with predominance of monocytes) and the true Schilling type (leukemic reticulo-endotheliosis), in which the cells are derived from the reticular cell. A primary autochthonous cutaneous origin for either type of monocytic leukemia may be encountered, a fact which we believe is not generally recognized by internists and pathologists or even by many dermatologists. One of us (H. M.)1 has previously emphasized the possible autochthonous cutaneous origin of any of the lymphoblastomas, including even myelogenous leukemia.2 It is not pertinent in this paper to discuss the various hemocytologic views regarding the monovalent, dualistic and trivalent origin of leukocytes.3 There is an increasing tendency in the recent literature to recognize two types of monocytic leukemia as well as the lymphatic and myelogenous types of leukemia. If one

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