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This monograph, consisting of eight chapters and sixteen case reports, is devoted to a broad consideration of the clinical entities in which cyanosis, pulmonary fibrosis, emphysema and failure of the right side of the heart, with or without sclerosis of the pulmonary artery, are manifested. The author gives syphilis little part in the pathogenesis of these states and blames chiefly chronic injury due to infections of the respiratory tract and noxious physical agents, such as dust and gases. It is clear that in Buenos Aires Ayerza's syndrome is considered much less an etiologic entity than a condition due to pathologic physiology. North American physicians are still puzzled over the apparently high incidence of "cor pulmone" in South America. The especial objective of the dissertation is the presentation of data and discussions on pathologic physiology of cyanosis, and this is achieved in splendid fashion. The clinical observations and physiologic measurements, including
La cianosis de los cardiacos negros de Ayerza: Su estudio semiológico, clínico y fisiopatológica.. Arch Intern Med (Chic). 1937;60(3):566. doi:10.1001/archinte.1937.00180030183020