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Article
August 1938

HYPERPARATHYROIDISM DUE TO IDIOPATHIC HYPERTROPHY (HYPERPLASIA?) OF PARATHYROID TISSUEFOLLOW-UP REPORT OF SIX CASES

Author Affiliations

BOSTON

From the Medical Service of the Massachusetts General Hospital and the Department of Medicine, Harvard Medical School.

Arch Intern Med (Chic). 1938;62(2):199-215. doi:10.1001/archinte.1938.00180130020002
Abstract

In 1934 the first paper on this subject from the clinic of the Massachusetts General Hospital was published.1 In that report three cases of hyperparathyroidism, from a series of nineteen cases of the condition in which the diagnosis was proved by operation, were cited in which pathologic examination showed what was then termed diffuse hyperplasia of all parathyroid tissue, rather than one or more circumscribed adenomas. It was pointed out that these cases represented a separate disease entity. Since that time the total number of cases of proved hyperparathyroidism at the Massachusetts General Hospital has increased to thirty-five, and the number of cases of "hyperplasia" has increased to six. As far as we are aware, a diagnosis of hyperplasia has not been made during life in other clinics, and these six patients remain a unique group. This paper is a follow-up report of the six cases. Some of the

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