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This book, a summary of the author's experience in the observation of rheumatic fever in the first three decades of life, is based on first hand information obtained from the study of 647 subjects selected from 1,000 patients.
The first chapter contains a short but interesting historical summary of rheumatic fever. In the second chapter the epidemiologic aspects of the disease are dealt with and effects of climate, season, economic status, contagion and heredity are considered. The author concurs in the opinion of the English commission that overcrowding and poverty are not prime factors in the determination of the incidence of rheumatic fever and states that there is no conclusive evidence of contagion in the production of the disease, "although many of the facts are consistent with this view." The most arresting observation relating to the epidemiologic aspects is that heredity plays an extremely significant role in the production of
Rheumatic Fever.. Arch Intern Med (Chic). 1941;67(5):1095–1096. doi:10.1001/archinte.1941.00200050203016