April 1942

Diseases of Nutrition

Arch Intern Med (Chic). 1942;69(4):717. doi:10.1001/archinte.1942.00200160168014

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On page 278 of the review "Diseases of Nutrition" by Drs. Butt, Leary and Wilder in the February issue (Arch. Int. Med.69:277, 1942) the manner of citation of a paper by Wolbach and Bessey (Vitamin A Deficiency and the Central Nervous System, Am. J. Path. 17:586 [July] 1941) implied that these authors stated vitamin A deficiency causes overgrowth of skeletal tissues. Actually they reported that in vitamin A deficiency in rats skeletal growth is retarded earlier than growth of the soft tissues in general, including that of the central nervous system. They have shown that in the white rat at least the nervous manifestations are due to pressure effects caused by the relative overgrowth of the central nervous system.

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