While subtotal thyroidectomy is a successful procedure in most patients with toxic goiter, it is followed in some instances by the persistence or recurrence of signs and symptoms of the disease. In a previous study one of us (W. O. T.) and associates1 reported observations on patients with postoperative thyrotoxicosis seen at the Massachusetts General Hospital, Boston. The present study was undertaken to compare the disease in an area in which simple goiter is prevalent (Chicago) with that in an area in which simple goiter is rare (Boston) and to secure further information concerning the cause, duration and types of postoperative thyrotoxicosis. It represents an analysis of data obtained on 294 patients with toxic goiter on whom subtotal thyroidectomy was performed and who were followed before and after operation in the endocrine clinic of the Presbyterian Hospital.
This study covers the ten year period 1930 to 1939.
PRESTON FW, THOMPSON WO. PERSISTENCE AND RECURRENCE OF TOXIC GOITER FOLLOWING SUBTOTAL THYROIDECTOMY. Arch Intern Med (Chic). 1942;69(6):1019-1039. doi:10.1001/archinte.1942.00200180090008