June 1942

Neural Mechanisms in Poliomyelitis.

Author Affiliations

By Howard A. Howe and David Bordian. Price, $3.50. Pp. 234, with 39 plates. New York: The Commonwealth Fund, 1942.

Arch Intern Med (Chic). 1942;69(6):1128. doi:10.1001/archinte.1942.00200180199015

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This important monograph by outstanding investigators in the field of poliomyelitis presents the evidence for transmission of virus on the basis both of original work and of review of the literature. The paramount importance of neural transmission even when the portal of entry is in the gastrointestinal tract is elucidated. In general, the relative importance of the respiratory tract and the alimentary tract as routes of invasion in different species of monkeys and in man is discussed, and gaps in knowledge not yet filled are pointed out. Of especial interest, of course, is the detailed account of the authors' own experiments, illustrated by many photomicrographs.

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