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Article
January 1944

THE MORGAGNI-STEWART-MOREL SYNDROMEREPORT OF A CASE WITH PNEUMOENCEPHALOGRAPHIC FINDINGS

Author Affiliations

PHILADELPHIA

From the Doctors Hospital.; ∥ From the University of Pennsylvania, Graduate School of Medicine.

Arch Intern Med (Chic). 1944;73(1):7-12. doi:10.1001/archinte.1944.00210130015002
Abstract

The symptom complex of hyperostosis frontalis interna, or its variants described by Sherwood Moore,1 with associated endocrine and neuropsychiatric manifestations, had stimulated a degree of interest, as evidenced by the increasing literature on the subject, to warrant the report of cases which may throw more light on the etiologic background of this interesting condition. The triad of hyperostosis frontalis interna, obesity and virilism had been described originally by Morgagni2 in 1765. Much later (1928) the appearance of a more careful study, by Stewart,3 in which he described the autopsy observations and added the clinical feature of a psychosis to the syndrome, and the first description of the syndrome as observed in a living person, by Morel4 in 1930, brought the group picture of calvarial hyperostosis and endocrine, metabolic and neuropsychiatric manifestations into clearer relief as an entity. Moore's elaborate work in reexamining roentgenograms of numerous human

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