[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.158.92.239. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
January 1944

CAPILLARY FRAGILITY IN RELATION TO DIABETES MELLITUS, HYPERTENSION AND AGE

Author Affiliations

MEDICAL CORPS, ARMY OF THE UNITED STATES; BOSTON

From the Medical and Surgical Services of the Beth Israel Hospital.

Arch Intern Med (Chic). 1944;73(1):18-22. doi:10.1001/archinte.1944.00210130026004
Abstract

In the course of investigating diabetic retinitis, many instances of increased capillary fragility were noted in the absence of blood dyscrasia or obvious vitamin C deficiency. For this reason it was considered important to investigate capillary fragility in diabetes, since the literature contains no record of such a study. Reported methods of determining this vascular abnormality vary so widely in technic and in interpretation that it was deemed necessary to evaluate the known methods before undertaking this investigation.

Capillary fragility is usually determined by one of two methods, either negative or positive pressure being used. The first method, introduced by Hecht,1 consists essentially in application of negative pressure over a standard area of skin for a given period of time. Most of the subsequent investigators2 have used a procedure in which a glass cup, 10 to 28 mm. in diameter at the mouth, is pressed for one minute

First Page Preview View Large
First page PDF preview
First page PDF preview
×