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Article
January 1944

RATE OF SEDIMENTATION OF ERYTHROCYTESS IN SICKLE CELL ANEMIA

Author Affiliations

NEW ORLEANS

From the Department of Medicine, School of Medicine, Tulane University, and Charity Hospital of Louisi

Arch Intern Med (Chic). 1944;73(1):41-52. doi:10.1001/archinte.1944.00210130049007
Abstract

Since the original description of sickle cell anemia, by Herrick1 in 1910, much has been written about this disease with little attention given to the problem of the sedimentation of the erythrocytes. A review of the literature since 1935 revealed 65 publications on sickle cell anemia. These articles contained 248 reports of cases, 149 being fairly detailed. In only 37 of these reports was the sedimentation rate mentioned. In 9 of the 37 the method used was not indicated, and in 24 there was no mention of the degree of anemia. Although these data are difficult to interpret, it would appear that in 7 instances the sedimentation rate was slow. Diggs2 recorded the sedimentation rate in 27 of a series of 37 cases and found it to be slow in manyinstances. He noted a decided variation even in the same subject. No attempt was made to explain these

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