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The sixth volume of the research studies of the Center of Investigation of the Tornu Hospital, under the direction of Prof. Roque A. Izzo, reflects a high caliber of work. Although it is essentially the product of a tuberculosis organization, including a painstaking hematometric study on normal and on tuberculous subjects by Mora and various pathologic studies of tuberculosis, cancer and miscellaneous topics by other members of the staff, the studies on the vitamin B complex by Costoya are outstanding in extent and thoroughness. After a painstaking review of the history, discovery, chemical constitution, preparation, pharmacology and standardization of the complex, the author focuses attention on methods of analysis and their practical application.
Although many principles have been used in analysis for vitamin B, the author was able to use the fluorescence produced by thiochrome developed from thiamine in blood and urine as a means of determining it. The readings
Publicaciones del Centro de Investigaciones Tisiologicas. Arch Intern Med (Chic). 1944;73(1):111. doi:10.1001/archinte.1944.00210130119012