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Article
September 1945

TULAREMIC MENINGITISREVIEW OF THE LITERATURE AND REPORT OF A CASE WITH POSTMORTEM OBSERVATIONS

Author Affiliations

NEW ORLEANS

From the Department of Medicine, Tulane University of Louisiana School of Medicine and Charity Hospital.

Arch Intern Med (Chic). 1945;76(3):163-166. doi:10.1001/archinte.1945.00210330034007
Abstract

Tularemia has been accepted generally as a systemic disease which frequently presents manifestations that may be interpreted as being septicemic in nature. It is logical, therefore, to suspect in case of a septicemic disease such as tularemia that almost every tissue of the body at some stage of the illness may be infected. Although evidence of meningeal irritation and involvement of the central nervous system are occasionally observed in cases of tularemia which terminate fatally, instances in which the existence of tularemic meningitis has been proved, either during life or by postmortem studies, are unusually rare, especially when one considers the frequency with which the lungs, liver, spleen and lymph nodes are involved in fatal cases of tularemia. Because invasion of the meninges by Bacterium tularense (Pasteurella tularensis) has been observed so infrequently, we have considered it worth while to report this case, which came to our attention in a

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