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Article
November 1945

The Specificity of Serological Reactions.

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By Karl Landsteiner, M.D. Second revised edition. Price, $5. Pp. 310. Cambridge, Mass.: Harvard University Press, 1945.

Arch Intern Med (Chic). 1945;76(5):397. doi:10.1001/archinte.1945.00210350143019

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Abstract

In 1936 the late Dr. Landsteiner published the first edition of his now classic monographic review of serologic reactions. The advances of the subsequent years made a revision desirable, and the text was completed at the time of Dr. Landsteiner's death; we are indebted to his son Ernest, also a physician, who undertook to see the revision carried through to the state of final publication.

This volume contains an excellent chapter on molecular structure and intermolecular forces as they apply to immunologic reactions, contributed by Dr. Linus Pauling. The remainder of the book includes an introductory section defining immunologic concepts and terminology and chapters on the serologic properties of various types of proteins, nonprotein cell substances and artificial conjugated antigens derived from simple chemical compounds, on cell antigens, on the nature and specificity of antibodies and on antigen-antibody reactions.

The enormous body of pertinent literature has been analyzed and built

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