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March 1947

Undersøgelser af insulinets virkning: specielt paa blodsukkeret og det respiratoriske stofskifte ved kulhydratrig og kulhydratfattig kost.

Arch Intern Med (Chic). 1947;79(3):363. doi:10.1001/archinte.1947.00220090123012

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The reviewer of this book is handicapped because his lack of reading knowledge of the Danish language limits his consideration of the monograph to its accompanying English summary and to a study of the charts and graphs.

Reported are observations on the effect of larger and smaller doses of insulin on a group of psychiatric patients given insulin for inducing hypoglycemic shock. The author regards these subjects as normal from the standpoint of metabolism and therefore considers that his observations are of general significance. They cover especially the effect of insulin and the induced hypoglycemia on the respiratory quotient with the subject subsisting on diets either high in carbohydrate (512 Gm.) or relatively low in carbohydrate (135 Gm.). He concludes that insulin inhibits hepatic glycogenolysis and that a diet poor in carbohydrate diminishes this inhibition.

Also considered are the changes effected by insulin in production of heat, respiration, ventilation and

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