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Article
March 1948

PRIMARY SYSTEMIC AMYLOIDOSIS SIMULATING CONSTRICTIVE PERICARDITISWith Steatorrhea and Hyperesthesia

Author Affiliations

CHICAGO

From the Department of Medicine, Division of Biological Sciences, University of Chicago.

Arch Intern Med (Chic). 1948;81(3):342-351. doi:10.1001/archinte.1948.00220210096009
Abstract

AMYLOIDOSIS has been divided into the following types: (1) that which is secondary to chronic suppurative diseases, tuberculosis and occasionally rheumatoid arthritis; (2) a type which sometimes accompanies multiple myeloma; (3) a form in which the amyloid is confined to one organ or tissue, and (4) primary systemic amyloidosis. The last-named type is distinctive in that: (1) it is not associated with suppuration, tuberculosis, rheumatoid arthritis or multiple myeloma; (2) it usually does not involve the liver, kidneys, adrenals or spleen to a marked degree; (3) the amyloid is deposited in the heart, lungs, gastrointestinal tract, mucous membranes, skin and striated muscles; (4) the amyloid is capricious in its staining reactions; (5) it often forms nodular amyloid tumors,1 and (6) patients afflicted with this disease live longer on an average than those with secondary amyloidosis.

This is the fifty-fourth reported case of primary systemic amyloidosis, a case which presents

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