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September 1948


Author Affiliations


From the Department of Pharmacology, University of Cape Town.

Arch Intern Med (Chic). 1948;82(3):263-309. doi:10.1001/archinte.1948.00220270048004
  1. Introduction

  2. Renal Hypertension

    • The Role of the Adrenal Cortex in the "Renal Pressor Mechanism"

  3. Changes in the Adrenal Cortex Associated with Hypertension in Man

    • Autopsy Studies

    • Biopsy and Clinical Studies

  4. Adrenal Cortex Hormones and Their Functions

    • Effect of Desoxycorticosterone in Man

    • Effect of Desoxycorticosterone in Animals

    • Effect of Other Hormones

    • a - c Bodies (Raab)

  5. Urinary Excretory Products of Adrenal Cortex Hormones as an Index of Adrenocortical Activity

    1. The Urinary 17-Ketosteroids

    2. Cortical-Like Material

    • Comparison of These Excretory Products

  6. Comment

    • The Renal Pressor Mechanism

    • The Role of the Adrenal Glands

    • The Hypothalamic-Pituitary Mechanism

    • The Basis of the Treatment of Hypertension

      1. Sympathectomy

      2. Thiocyanate Therapy

      3. Nonspecific or Inflammatory Reactions

  7. Summary of Reports Indicating the Significance of the Adrenal Cortex in Arterial Hypertension

A. INTRODUCTION  Increased arterial blood pressure of known or suspected origin is an extremely common sign, listed in association with at

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