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Article
March 1950

HYPERTENSIVE CARDIOVASCULAR DISEASE (ACUTE) (MALIGNANT HYPERTENSION)Clinical and Pathologic Study of Thirty-Nine Cases

Author Affiliations

MILWAUKEE

From the Departments of Medicine and Pathology, Marquette University School of Medicine and Milwaukee County Hospital.

Arch Intern Med (Chic). 1950;85(3):432-458. doi:10.1001/archinte.1950.00230090069005
Abstract

THERE is no unanimity of opinion regarding the proper place in the classification of hypertensive cardiovascular disease of the acute form, often called malignant hypertension, and there are even some writers who have stated that the term should be dropped entirely. The confusion regarding nomenclature in the study of this condition has led some to believe that malignant hypertension is a disease sui generis, unrelated to other forms of hypertensive cardiovascular disease. From the observations of one of us (F. D. M.) and an associate, published previously,1 it was our opinion at that time that malignant hypertension did not differ in kind from benign hypertensive cardiovascular disease but that the difference was merely one of degree. In this study we changed our mind regarding the course, the prognosis and the treatment of malignant hypertension.

For the purpose of this paper, 39 cases of malignant hypertension were studied clinically and

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