[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.158.127.188. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
July 1950

CLUBBING OF DIGITS, METAPLASIA OF URINARY BLADDER AND MUCOUS DIARRHEA

Author Affiliations

WEST ROXBURY, MASS.

From the Medical, Urological and Pathological Services, Veterans Administration Hospital.

Arch Intern Med (Chic). 1950;86(1):10-21. doi:10.1001/archinte.1950.00230130032002
Abstract

THE ASSOCIATION of clubbing of the fingers with various disease states has interested physicians for many years. Little is known about the pathogenesis of this disturbance. Mendlowitz1 carefully analyzed all reports of the syndrome in 1942 and grouped all bilateral symmetric cases as acquired, hereditary or idiopathic. The acquired condition was associated with certain pulmonary, cardiac and gastrointestinal disorders and a rarely seen miscellaneous group of diseases. In this last classification was recorded a single case of cystopyelitis, but no other urologic aspects were discussed. The hereditary group was considered to be a separate entity, inherited as a mendelian dominant trait and therefore often affecting other members of the family. In these persons the clubbing appeared early in life, and its association with various diseases was, in Mendlowitz' opinion, simply coincidental. In the so-called idiopathic group a single case associated with urologic abnormalities was cited but not discussed. Mendlowitz

First Page Preview View Large
First page PDF preview
First page PDF preview
×