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November 1950

RIEHL'S MELANOSIS AND THE ADRENAL GLANDS

Author Affiliations

LONDON, ENGLAND

From the Department of Physiology, Middlesex Hospital Medical School.

AMA Arch Intern Med. 1950;86(5):682-690. doi:10.1001/archinte.1950.00230170035004
Abstract

A CASE OF Riehl's melanosis was attributed1 to adrenal insufficiency resulting from the protracted ingestion of toxic amounts of fluorine which sensitized the skin to the action of the sun's rays. Treatment directed against chronic fluorine poisoning led to the disappearance of the facial pigmentation and of the coexistent patches of melanoderma on various parts of the body.

In the following paragraphs another case of Riehl's melanosis is recorded.

REPORT OF A CASE  A retired civil servant, aged 66, was from his boyhood subject to frequent attacks of a condition diagnosed as "influenza," which recurred three or four times a year. Laryngitis was a frequent complication, and an attack in 1946 left him with the loss of the senses of smell and taste. He never recovered the former, but the latter improved, though without ever returning to normal. The underlying cause of the hyperpyrexia was never discovered, and several

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