[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.146.169.191. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
March 1951

TITRATED, REGULARLY SPACED RADIOACTIVE PHOSPHORUS OR SPRAY ROENTGEN THERAPY OF LEUKEMIAS

Author Affiliations

PORTLAND, ORE.

From the Division of Experimental Medicine, Department of Medicine, University of Oregon Medical School.

AMA Arch Intern Med. 1951;87(3):329-348. doi:10.1001/archinte.1951.03810030002001
Abstract

THE EVALUATION of a new therapy for chronic leukemias is difficult because of the diverse course of untreated patients, the differing stages of the disease when patients are first seen by a physician, the frequent uncertainty concerning the correct date of onset and the presence of other variables making comparison with published data on other series of patients less satisfactory than the ideally designed experiment. Yet, with a treatment that seems to be giving comfort and years of essentially normal living, the use of alternate or randomly selected, untreated controls in so serious a disease seems unjustified.

It is the purpose of this paper to present the principles of a treatment in use since 1941 in sufficient detail that others may be able to use it and to present enough of the evidence of its merits that others may choose to aid in its final evaluation. This of necessity will

First Page Preview View Large
First page PDF preview
First page PDF preview
×