March 1951


Author Affiliations


From the Departments of Internal Medicine and Pathology of Veterans Administration Hospital, Wood, Wis., Marquette University School of Medicine and the Department of Internal Medicine, Milwaukee County Hospital, Wauwatosa, Wis.

AMA Arch Intern Med. 1951;87(3):391-409. doi:10.1001/archinte.1951.03810030064006

PANCREATIC calcification is a disease entity with a distinct clinical and pathological picture. It must be considered as a possibility in the differential diagnosis of abdominal pain. When the condition is looked for carefully by means of roentgenography, the diagnosis can be established in a greater number of cases than previously reported. Since there are few laboratory findings other than roentgenographic appearance and changes in the serum amylase level to help localize the disease to the pancreas, it is imperative that accurate history, physical examination and clinical judgment be used to help make a positive diagnosis.

Description of stones in the pancreas excited the interest of physicians as early as the seventeenth century. DeGraaf1 spoke of the condition in 1667. Oser2 stated that this report was followed by the publications of Bonetus in 1700, Galeati in 1757 and Morgagni in 1765. Thomas Cowley, also cited by Oser,2

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