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Article
August 1951

CHOROIDAL LESION IN ACUTE BRUCELLOSIS WHICH RESPONDED TO STREPTOMYCIN AND SULFADIAZINE

Author Affiliations

TOPEKA, KAN.

From Winter Veterans Administration Hospital. Dr. Swan is from the Medical Service. Dr. McClellan is from the Ophthalmological Service. Dr. Reizman is former resident in internal medicine.

AMA Arch Intern Med. 1951;88(2):258-261. doi:10.1001/archinte.1951.03810080126013
Abstract

BRUCELLOSIS may be a widely disseminated disease in which lesions of the eye not infrequently occur. Green,1 in a review of the eye lesions associated with brucellosis, collected 28 cases from the literature and added four of his own. The retina, optic nerve, uveal tract, cornea and ocular muscles were involved. Treatment of the primary disease has been more effective since the newer chemotherapeutic and antibiotic agents have been introduced.

Woods,2 discussing the treatment of ocular brucellosis, states:

Streptomycin has some action. It has recently been shown in experimental animals that the combination of streptomycin and sulfadiazine has a greater therapeutic action than might be expected by mere summation. Such treatment has not yet been employed in human chronic infections to allow valid conclusions to be drawn.

This paper describes a case which responded satisfactorily to combined streptomycin and sulfadiazine therapy.

REPORT OF A CASE  A 21 year

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