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A surprising amount of useful information is encompassed in this small volume, yet it suffers from the usual shortcomings of a small manual. The material is given almost in outline form, with so little discussion of the pros and cons of the issues that the uncritical reader might fall into many pitfalls if this book were his only source of information. For instance, after a short but fairly adequate discussion of the diagnosis of the "Collagen Diseases," the statement is made: "Benadryl may have some rational place in the treatment of the usually hopeless condition, since the three patients are alive and apparently symptom free." Which collagen disease was being treated is not mentioned, and no mention of the use of ACTH, cortisone or p-aminobenzoic acid in the treatment of these disorders is made in this section.
Later on in the section on the use of cortisone and ACTH,
Manual of Rheumatic Diseases.. AMA Arch Intern Med. 1951;88(2):270. doi:10.1001/archinte.1951.03810080138029