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This book is nothing more than an annotated bibliography on bacitracin. It contains a few statements that embrace generalities concerning antibiotic agents which are good. It is obviously a conspicuous effort to make bacitracin look better than it actually is from the standpoint of antibiotic therapy. The volume does not emphasize the nephrotoxic properties of bacitracin which seriously limit the use of this antibiotic in clinical medicine. On the contrary, the nephrotoxicity of this agent is deprecated, and efforts are made in certain portions of the book to explain nephrotoxicity on a basis other than that of the drug itself. Contrary to what is said in this work, bacitracin is hardly the drug of choice in the treatment of amebiasis. It certainly is of little or no value, despite the authors' contentions, in the treatment of ulcerative colitis and in the preoperative preparation of patients for operations on the bowel.
Bacitracin.. AMA Arch Intern Med. 1952;90(3):424. doi:10.1001/archinte.1952.00240090145019