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March 1954

The Diabetic Neuropathies.

AMA Arch Intern Med. 1954;93(3):479. doi:10.1001/archinte.1954.00240270165027

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This monograph presents the results of a group study on 162 cases of diabetic neuropathy among 261 diabetic patients. The material is well arranged and gives a brief but excellent description of symptomatology, clinical types, theories of pathogenesis, pathology, course and prognosis, differential diagnosis, and treatment. There are a good summary, an excellent bibliography, and index. The format is attractive.

As to pathogenesis, the various theories are reviewed—arteriosclerosis, vitamin or other dietary deficiency, unknown intermediate metabolites with toxic action on nerves, etc. The last is given preference because of the relationship of neuropathy to poor control of diabetes and malnutrition. Ischemic neuropathy was rarely found.

Treatment emphasizes adequate control of diabetes and the usual symptomatic measures.

While there is nothing original in this volume, it is an excellent review of the subject.

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