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The problem of perplexing fever assails the specialist in internal medicine and the physician in general practice. At one time or another it confronts every practising physician. This book by Keefer and Leard fills a long-felt need for a systematic treatise analyzing the problem of the patient with obscure fever. From their rich clinical experience and from a review of the now substantial literature they have culled many useful facts. The presentation of numerous case reports gives a good demonstration of the many types of problem and their final solution. One gets the impression from such a study that all the cases are solved, which is far from true. Many patients recover without any solution. Others may die without having the diagnosis discovered during life or at autopsy. Specific infections still head the list, but the pattern of puzzling fever that one encounters in contemporary practice has shifted dramatically over
Prolonged and Perplexing Fevers.. AMA Arch Intern Med. 1956;97(1):113-114. doi:10.1001/archinte.1956.00250190129023