Candida albicans and related organisms rarely produce septicemia and widespread lesions which can be considered the immediate cause of death. The patient reported here developed C. albicans septicemia while recovering from severe pancreatitis. Broadspectrum antibiotics given during the acute episode of pancreatitis probably allowed this organism to establish itself in necrotic areas of the pancreas and peripancreatic tissues. Oral nystatin* therapy failed to influence the rapidly fatal septic course.
Report of a Case
A 68-year-old single, white, retired laborer was admitted to the King County Hospital on Sept. 18, 1955, complaining of severe pain throughout the abdomen of 14 hours' duration. He had also noted low back pain and had vomited several times. He recalled two similar episodes within the preceding two years, but otherwise had been in good health. No dietary or alcoholic excess preceded the onset of abdominal pain.The patient was moderately obese and appeared acutely ill.
BARRETT B, VOLWILER W, KIRBY WMM, JENSEN CR. Fatal Systemic Moniliasis Following Pancreatitis. AMA Arch Intern Med. 1957;99(2):209-213. doi:10.1001/archinte.1957.00260020045007