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March 1959

The Urine Remains the SameCurrent and Countercurrent Concepts in Renal Physiology

Author Affiliations


From the Medical Service and Research Laboratory, Boston Veterans Administration Hospital, and the Departments of Medicine, Boston University School of Medicine and Tufts University School of Medicine.

AMA Arch Intern Med. 1959;103(3):489-494. doi:10.1001/archinte.1959.00270030145014

The following letter of transmission accompanied Dr. Strauss' article. Hoping our readers will find in it a hearty chuckle, as we did, we share it with you. P. S. R.

"I am enclosing my introduction for the three papers on renal physiology. The title derives from a Greek inscription which possibly may be construed to mean 'old urine in new kidneys.' When the Permian Puddingstone rock formation was being excavated for the foundation of our hospital this inscription was found on a sheet of membranous material, faintly ruled in semilogarithmic fashion, which was unearthed. The membrane, while being prepared for C" analysis to determine its age was unfortunately burnt to an ash, analysis of which is consistent with the hypothesis that the membrane had once been saturated with late Paleozoic urine. M. B. S."

Although the history of renal physiology may be said to begin with Ludwig a little over