The increasing prevalence of nickel sensitivity in recent years has been emphasized by many investigators.* Most of these investigators have directed attention primarily to the dermatologic manifestations of sensitization to nickel; however, it is noteworthy that other allergic phenomena may also be encountered. Within the past year Arvidsson and Bogg1 published a case report which indicated an association between Löffler's syndrome and acute nickel dermatitis. This publication has stimulated us to report a second case of Löffler's syndrome (pulmonary eosinophilia) in association -with severe nickel sensitivity.
Report of Case
The patient is a chemical engineer, aged 52 years, who was employed for several years in the design and development of an industrial plant manufacturing nickel carbonyl. The plant was constructed in a distant city in 1952, and during the first 6 months of the plant's operation, the patient was engaged in direct supervision of nickel carbonyl production. During these
SUNDERMAN FW, SUNDERMAN FW. Loffler's Syndrome Associated with Nickel Sensitivity. Arch Intern Med. 1961;107(3):405-408. doi:10.1001/archinte.1961.03620030093014