July 1961

Cirrhosis of the Liver in Iran

Author Affiliations


From the Departments of Medicine and Biochemistry, Shiraz University Medical Center, Iran.; Present address: Assistant Professor of Medicine, Vanderbilt University, c/o Naval American Research Unit 3, American Embassy, Cairo, U.A.R. (Dr. Prasad); University of Kentucky Medical Center, Lexington, Ky. (Dr. Halsted); Department of Chemistry, University of Birmingham, England (Dr. Walker).; Visiting Associate Professor of Medicine, University of Shiraz, Iran, and Associate in Medicine, Nemazee Hospital (Dr. Prasad); Professor of Biochemistry, Faculty of Medicine, University of Shiraz (Dr. Walker); Instructor in Medicine, University of Shiraz (Dr. Dehgani); Visiting Fulbright Professor and acting Chairman, Department of Medicine, University of Shiraz, and Chief of Medical Service, Nemazee Hospital (Dr. Halsted).

Arch Intern Med. 1961;108(1):100-108. doi:10.1001/archinte.1961.03620070102013

Introduction  Cirrhosis of the liver is a particularly common clinical problem in Iran. The frequent association of cirrhosis in the western world with alcoholism is very rare in this country, and certain other clinical differences appear to exist. Malnutrition exists extensively in the villages although it is difficult to establish a specific relationship of this to the genesis of cirrhosis. Sporadic cases are accounted for by accepted etiologic factors such as hemochromatosis, Wilson's disease, biliary cirrhosis, etc., but in the majority of patients, the cause remains obscure. To our knowledge no study has been reported on this subject from Iran. The purpose of this paper is to document clinical, hematologic, biochemical, and histologic findings in patients with cirrhosis of the liver and briefly to compare these findings with those noted in certain other parts of the world.

Methods  Thirty-nine patients were studied. They represented patients who were admitted to either

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