November 1963

Elevated Sweat Sodium and Chloride in Adult Without Cystic Fibrosis

Author Affiliations


Department of Medicine (Capt Gup); Chief, Gastroenterology Service (Lt Col Briggs).; Department of Medicine, Fitzsimons General Hospital, Denver.

Arch Intern Med. 1963;112(5):699-701. doi:10.1001/archinte.1963.03860050086008

Cystic fibrosis of the pancreas is a systemic disease affecting the pancreas, liver, lungs, salivary glands, and sweat glands. Although well recognized in infants and children, it has been infrequently reported in patients beyond the pediatric age group. A number of authors have placed considerable significance on sweat sodium and chloride levels above 60 mEq/liter in the diagnosis of cystic fibrosis in adults. This has been particularly true in attempting to find an underlying etiology for various respiratory diseases. Anderson et al1 do not believe that sweat sodium and chloride levels in adults can be used to show a significant relationship between various respiratory diseases and cystic fibrosis of the pancreas.

The purpose of this paper is to report a patient with heat intolerance, with elevated sweat sodium and chloride levels, without adrenal insufficiency or evidence of cystic fibrosis of the pancreas.

Report of a Case  An 18-year-old white

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