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This is a comprehensive monograph for medical practitioners and for those in other disciplines interested in problems of the elderly. There are 26 contributors to the 23 chapters. The difficulty of making absolute statements about drug effects in old age is still present. The double-blind procedure has taken all the joy out of free-wheeling impressions in therapeutics. Drug-induced disability is more likely in the aged because they do not have the reserves so often fortunately present in younger individuals. The need for continuing and careful observation of the patient is stressed again and again. Individual variation is probably greater among the aged themselves than variation between the aged and the middle aged. The rather common presence of other chronic disease in the aged serves also to complicate the picture. The general indications for the use of drugs are the same as in younger age groups, but doses are usually smaller
Ossenfort WF. Clinical Principles and Drugs in the Aging.. Arch Intern Med. 1963;112(5):806-807. doi:10.1001/archinte.1963.03860050193052