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Article
November 1964

Intermittent Dialysis in Chronic Uremia

Author Affiliations

CHICAGO

Fellow, Clinical Research Center, 1962-1963 (Dr. Smith); Instructor in Medicine, Northwestern University Medical School, Adjunct Attending Physician, Passavant Memorial Hospital (Dr. Simon); Assistant Professor of Medicine, Northwestern University Medical School, Adjunct Attending Physician and Director, Clinical Research Center, Passavant Memorial Hospital (Dr. del Greco).

From the Department of Medicine, Passavant Memorial Hospital and Northwestern University Medical School.

Arch Intern Med. 1964;114(5):610-615. doi:10.1001/archinte.1964.03860110080005
Abstract

In the course of the past 15 years, dialysis has been employed with increasing frequency for treating patients with chronic renal failure. Acknowledged indications for dialysis include rapid deterioration caused by an intercurrent illness or acute exacerbation of the underlying disease, and relief of azotemia before surgery.1-3 More recently, dialysis has been employed in the management of patients with end-stage kidney disease.4,5 A significant prolongation of life has been obtained in a few patients by a program of "periodic" dialyses performed at intervals of three to seven days.6 Unfortunately, this type of therapy has so many drawbacks and is so costly that it can be made available to a very small minority of carefully selected patients.

An alternate approach to the therapy of advanced, chronic renal failure is to employ dialysis on an "intermittent" basis, whenever medical management alone fails to produce relief of uremia. The present

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