March 1965

Balloon Radioautography in Differentiation of Benign and Malignant Gastric Lesions

Author Affiliations


From the departments of radiology and gastroenterology of the Graduate Hospital of the University of Pennsylvania. Professor of Clinical Radiology, Schools of Medicine, University of Pennsylvania, and Associate Radiologist, Graduate Hospital of the University of Pennsylvania (Dr. Stein); Instructor in Gastroenterology (Dr. Tachdjian), and Instructor in Radiology (Dr. Magid), Graduate School of Medicine, University of Pennsylvania; Director of Escuela de Pathològia Digestiva Hospital de la Santa Cruz y San Pablo, Barcelona, Spain (Dr. Vilardell).

Arch Intern Med. 1965;115(3):326-329. doi:10.1001/archinte.1965.03860150070013

I. Introduction  THAT various malignant tumors can selectively concentrate phosphorus (utilizing radioactive 32P as a label) has been well documented by many authors.1-4 In general, in vivo evaluation of 32P concentration in neoplastic lesions had been limited to readily accessible tumors which could be counted directly with Geiger-Müller probes. Nakayama 4 did explore in vivo counting of esophageal and gastric neoplasms with considerable success.In 1960, Ackerman and his associates 5 described a new radioautographic technique to permit in vivo detection of gastric neoplasms. After the intravenous administration of 32P, a rubber balloon coated with a photosensitive emulsion is introduced into the stomach. The degree of darkening of the photosensitive surface of the balloon is a measure of the degree of radioactivity of the stomach.The accuracy of balloon radioautography in the differentiation of benign and malignant gastric lesions in comparison with the accuracy of exfoliative

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