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March 1965

CNS Sarcoid Granuloma Monitored by Brain Scanning

Author Affiliations


From the Department of Medicine (Neurology) and Radiology, University of Pittsburgh School of Medicine.

Arch Intern Med. 1965;115(3):336-338. doi:10.1001/archinte.1965.03860150080015

PARENCHYMATOUS involvement of the nervous system in sarcoidosis is an infrequent occurrence. Furthermore, the use of radioisotopic tracer substances in the diagnosis of non-neoplastic brain lesions is less well known than their utilization in tumor diagnosis. These two phenomena are illustrated in the following case.

Report of Case  A 41-year-old white woman was relatively well until Jan 2, 1964. While raising her left arm in voluntary activity, she experienced the onset of clonic movements of the left upper extremity. This was soon followed by four hours of unconsciousness, unaccompanied by a generalized motor seizure. Over the ensuing few weeks, she noted a 20 lb (9.1 kg) weight loss and frequent diffuse dull headaches. Review of systems and past history were unremarkable except for one episode of "pleurisy" of ten days' duration the previous winter and questionable recent hemoptysis.Upon admission to the Presbyterian-University Hospital on Jan 23, 1964, she did

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