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March 1965

Antibiotic and Chemotherapy.

Author Affiliations

By Mary Barber and Lawrence P. Garrod. Price, $8. Pp 366. E. & S. Livingstone, Ltd., Edinburgh, distributed by Williams & Wilkins Co., 428 Preston St, Baltimore, Md 21202, 1963.

Arch Intern Med. 1965;115(3):366. doi:10.1001/archinte.1965.03860150110028

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This concise, authoritative, and practical book on the use of sulfonamides and antibiotic agents in the treatment of infections is a welcome treatise and should be readily available to every student and practitioner of medicine. It comes at a time when progress in this field has reached a point when successful chemotherapy of infections requires a thorough understanding of the drugs available and the methods for their most effective use.

It was written by two authorities on the subject who have themselves continually made significant contributions to the "golden era of chemotherapy." Professor Garrod, having already worked with the sulfonamides, participated in the early development of methods for penicillin assay and in vitro sensitivity tests and described its antibacterial effect when applied locally. Dr. Barber first reported the effect of inoculum size on penicillin activity and made the observation in 1947 that strains of staphylococci relatively resistant to penicillin were

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