July 1965

Aetiology of Diabetes Mellitus and Its Complications.

Author Affiliations

Edited by M. P. Cameron and M. O'Connor. Price, $12.50. Pp 405. Little, Brown & Co., 34 Beacon St, Boston, Mass 02106, 1964.

Arch Intern Med. 1965;116(1):156. doi:10.1001/archinte.1965.03870010158029

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The 15th Ciba Foundation Colloquium on Endocrinology, held in England in October 1963, was organized to review information pertaining to the pathogenesis of diabetes mellitus and its complications, particularly with respect to human rather than experimental disease. The small but distinguished list of guests, naturally somewhat weighted with representatives from Great Britain, includes many of the best-known names in the field.

The volume opens with chapters on the epidemiology of diabetes by Walker and the genetic aspects of diabetes in the Chinese hamster by Yerganian. Ogilvie and Lacy contribute descriptions of the morphology of the diabetic pancreas and its beta cells. A section on the biosynthesis and secretion of insulin includes chapters by Taylor, Renold, Fajans, and Randle. Renold and Hales write on plasma insulin, and various types of insulin antagonism are discussed by Kipnis, Randle, Vallance-Owen, Bornstein, and Butterfield. Chapters on the biochemistry of blood vessels by Muir and

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