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August 1965

Myxedema Coma.

Arch Intern Med. 1965;116(2):311. doi:10.1001/archinte.1965.03870020151034

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This little monograph about a rare but disastrous state pulls together, for the first time, the published experience of the Western world. From that point of view it is a useful source for reference. At the same time, the pulling together of a profusion of opinions regarding the pathogenesis, clinical manifestations, and treatment of myxedema coma leads to confusion. Perhaps this is useful to the extent that it indicates our ignorance about many aspects of the pathologic physiology of myxedema coma and points out areas that need research.

While one might argue about the pertinence of some aspects of the pathophysiology and of the treatment of myxedema coma, reading of the chapters on these topics will prove informative. Of particular value are the few pages devoted to complications. The bizarre ways in which myxedema coma can present and the seemingly unrelated complications that may arise are worthy of every clinician's

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