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September 1965

Cavitary Sarcoidosis of the Lung

Author Affiliations


From the Department of Medicine, University of Colorado School of Medicine (Resident in Medicine: Dr. Hamilton; Assistant Professor of Medicine: Dr. Petty Instructor in Pathology: Dr. Haiby); Webb-Waring Institute for Medical Research; and the Department of Pathology, Denver Veterans Administration Hospital.

Arch Intern Med. 1965;116(3):428-430. doi:10.1001/archinte.1965.03870030108018

SARCOIDOSIS is considered a noncaseating and hence a noncavitating granulomatous process. Cavitary lesions are occasionally observed in sarcoidosis and have been ascribed to intercurrent fungal, tuberculous, or pyogenic infections.1-4 Concomitant bronchiectasis or bullous emphysema can also simulate cavitation, as shown on chest roentgenograms.5

Cavitation in pulmonary sarcoid granulomas has been previously reported.6-11 Since, however, specific studies to rule out known infectious causes of cavitating pulmonary granulomas were lacking or incomplete in these reports, the diagnosis of sarcoidosis may be challenged in all but one report.9

It is the purpose of this communication to report a case of cavitation of a pulmonary sarcoid granuloma. Bacteriologic and serologic studies adequately excluded the possibility of an infectious cause of this cavitary granuloma.

Report of a Case  A 30-year-old Negro man was admitted to the Denver Veterans Administration Hospital for the first time in June 1957. A three-year history of repeated episodes of fever,

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