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Article
December 1965

Functioning Pancreatic Islet-Cell Adenoma Diagnosed Preoperatively by Means of Splanchnic Arteriography

Author Affiliations

CLEVELAND

From the departments of hospital radiology, endocrinology, and general surgery, the Cleveland Clinic Foundation, Cleveland.

Arch Intern Med. 1965;116(6):824-827. doi:10.1001/archinte.1965.03870060022005
Abstract

THE DIAGNOSIS OF organic hypoglycemia due to an intraabdominal tumor usually can be made on the basis of clinical criteria. A high value of fasting plasma insulin may be helpful in differentiating a functioning islet-cell tumor of the pancreas from an intraabdominal fibrosarcoma, however, the value is normal in some patients with functioning β-cell tumor of the pancreas.1 Even when the presence of hyperinsulinism has been determined, there remains the often difficult surgical problem of locating the functioning islet-cell tumor, particularly if the tumor is in the head of the pancreas. A method that demonstrates the presence and location of a functioning islet-cell tumor of the pancreas preoperatively would make the task of the surgeon much easier.

The purpose of this paper is to report a case of proved organic hypoglycemia in which a functioning islet-cell adenoma of the pancreas was preoperatively diagnosed and located by means of selective

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