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January 1966

Actinobacillus Actinomycetemcomitans Endocarditis

Author Affiliations


From the Department of Internal Medicine, University of Michigan, and Veterans Administration Hospital, Ann Arbor.

Arch Intern Med. 1966;117(1):99-102. doi:10.1001/archinte.1966.03870070113017

IN 1912, Kilinger first described Actinobacillus actinomycetemcomitans as a bacterial organism occurring in close association with active cases of actinomycosis. Thjøtta and Sydves in 1951 reported the first case of human infection in which this organism was the sole infecting agent.1 King and Tatum have reported cultural and serological studies on A actinomycetemcomitans identified from blood cultures in 27 instances, but the sources of infection were not described.2 A review of the literature has failed to reveal a case of A actinomycetemcomitans endocarditis. It is our purpose to present such a case with bacteriologic and pathologic material and to reemphasize the similarity of this organism to Hemophilus aphrophilus.

Report of Case  A 57-year-old Negro (0-14521) was admitted to the Ann Arbor Veterans Administration Hospital on June 11, 1964. Four months earlier he had begun experiencing fatigue, weakness, fever, and nocturnal diaphoresis. Hospitalization elsewhere revealed a hemoglobin level of

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