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Appropriately dedicated to W. F. Hamilton, the pioneer in the exploration of circulation time, volume, and pathways by means of dye-dilution, this book by Hegglin and collaborators from the University of Zürich examines new colorimetric methods available for measuring the function of the circulatory system and for detecting its defects. New apparatus and new techniques are coming into the hands of investigators so rapidly that the investigator himself is sorely tried to keep up with progress and may fail to gain all the information that can be obtained or to appreciate the inherent limitations of the method. The clinician is likely to be left far behind.
The authors gather information about dyedilution techniques and present it simply and systematically. The first half covers technical details, the indicator-dilution curve, circulation time, plasma volume, cardiac ejection, and the distribution of blood into the central and peripheral compartments. The last half considers specific
Wehrmacher WH. Kreislaufdiagnostik mit der Farbstoffverdünnungsmethode.. Arch Intern Med. 1966;117(3):460. doi:10.1001/archinte.1966.03870090144031