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May 1966

Renal Function and Renal Failure.

Arch Intern Med. 1966;117(5):733. doi:10.1001/archinte.1966.03870110125035

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


The author is Chief of the Medical Service at the Veterans Administration West Side Hospital in Chicago and Associate Professor of Medicine at the University of Illinois. This book is an extension of the lectures given to third-year medical students at the University.

Doctor Bernstein has utilized a most ingenious approach to the subject. He starts with normal renal function, and by using simple, clear diagrams explains the physiology of the nephron at different sites. He goes on to discuss the methods of formation of different solutions of water and electrolytes, and the remarkable ability of the kidney to adapt itself to wide physiologic variations. The author then presents a working concept of renal reserve which he ties in with a discussion of body composition and the differential diagnosis of azotemia. In the final chapter, there are discussions of fluid and electrolyte replacement therapy and of derangements in ion concentrations.

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