June 1966

Heart Block in Ankylosing Spondylitis

Author Affiliations


From the departments of medicine and pathology, University of Washington School of Medicine, Seattle.

Arch Intern Med. 1966;117(6):800-806. doi:10.1001/archinte.1966.03870120064013

A DISTINCTIVE type of aortitis causing isolated aortic insufficiency in patients with ankylosing spondylitis has been the subject of several reports 1-11 since the association was first noted by Bauer et al in 1951.12 Atrioventricular (A-V) and intraventricular conduction defects have been cited but seldom stressed.1,2,4-6,9,11,13 The majority of cases has shown first degree atrioventricular block with an occasional left bundle branch block. There have been two reports of complete heart block. Bernstein 13 briefly reported two patients with aortic insufficiency and third degree block while Sobin and Hagstrom 6 demonstrated that the pathological process involved both the aortic root and the ventricular conduction system.

Report of Cases  Two cases of spondylitic aortitis with conduction defects were recently seen by us. Case 1 is the second case in the English language literature of proved pathologic involvement of the bundle of His in spondylitic aortitis associated with a conduction

First Page Preview View Large
First page PDF preview
First page PDF preview