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July 1966

Diabetes Insipidus Following Post-Partum Shock

Author Affiliations


From the Department of Medicine, Symmes Hospital, Arlington, Mass, the Department of Medicine and Evans Memorial Research Laboratories, University Hospital, and the Boston University School of Medicine.

Arch Intern Med. 1966;118(1):9-13. doi:10.1001/archinte.1966.00290130011003

Diabetes INSIPIDUS has been described as a very rare accompaniment of Sheehan's syndrome.1-7 We recently encountered a patient in whom transient diabetes insipidus was recognized relatively early in the puerperium.

Report of a Case  A 30-year-old housewife, gravida 2, para 1, entered the Symmes Hospital on June 19, 1964, for routine induction. She had only one hour of labor and was delivered of a full-term, normal infant. Massive hemorrhage followed, and hypofibrinogenemia was demonstrated (blood fibrinogen level, 52 mg/100 cc normal, 250-400 mg/100 cc. Over the next several hours she received 4 units of blood and 6 units of fibrinogen. She was in profound shock for a period of 4½ hours manifested by pallor, marked diaphoresis, therapy to absent peripheral pulses, and a systolic blood pressure of 0 to 80 mm Hg. Urine output was between 200 and 400 ml/24 hr during the first three hospital days, increased to

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