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Although only infrequently recognized, Toxoplasma gondii (Nicolle and Manceaux, 1908) probably invades at least as many people as tuberculosis. Kirchhoff and Kraeubig have tapped the pooled knowledge of German and Austrian experts in parasitology, pathology, immunology, pediatrics, gynecology and obstetrics, ophthalmology, and public health and they have condensed their combined knowledge of toxoplasmosis in a little volume. It should help the clinician recognize it more frequently.
Since most internists are likely to recognize toxoplasmosis only among cases resembling infectious mononucleosis with negative heterophil reactions, the thoroughgoing descriptions presented of the clinical manifestations may be particularly interesting: manifestations of the acute disease include lymphadenitis particularly in the neck, severe persistent headache particularly in the forehead, nonspecific fever, meningismus, splenomegaly, hepatomegaly rarely with hepatitis, transient exanthemata, retinitis, conjunctivitis, vesicular pharyngitis, endometritis, and miscarriage or stillbirth. Manifestations of the chronic disease include intermittent fever often preceded or accompanied by peripheral muscular or articular
Wehrmacher WH. Toxoplasmose: Praktische Fragen und Ergebnisse.. Arch Intern Med. 1966;118(1):94-95. doi:10.1001/archinte.1966.00290130096026