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At the outset, the authors point out that most scientific studies on the metabolism of alcohol are made wih alcohol itself. But in real life by real people, they continue, alcohol is not ingested as such, but in the form of whiskey, wine, beer, and other available forms. Therefore, they reason, there can be no one-to-one correspondence of effect between alcohol and its beverages—though that can be disputed. However, the setting in which alcoholic drinks are consumed differs from the laboratory ingestion of diluted alcohol, and its influence may thus be modified. Other aspects which will influence the effect of alcohol are total dose; rate at which it is consumed, converted, and excreted; plus collateral factors such as food intake. But while we do not, as far as I am aware, have a critical study of the comparative effect of alcoholic beverages (as against alcohol) there is an immense amount
Di Cyan E. Alcoholic Beverages in Clinical Medicine.. Arch Intern Med. 1967;119(5):539–540. doi:10.1001/archinte.1967.00290230177016