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Doctor Berkowitz has produced an unusual book on diagnosis. What he has done has been to list a series of symptoms and signs, such as jaundice, nausea, vomiting, or menstrual disorders, and then to check for all the conditions that might produce these particular clinical findings. This book could be helpful to a physician faced with a much-studied patient who complains, let us say, of severe itching day and night, with no other symptoms or helpful findings. He could look to this book and immediately identify the disorders that he should suspect (such as the very subtle jaundice due to cancer of the liver or the final stage of Hodgkin's disease or a beginning diabetes).
I was able to use this book the other day when a young woman came in having a history of daily slight fever for months and no other clues that would help in the diagnosis.
Alvarez WC. Differential Diagnosis: A Memory Stimulus System for Pocket, Punchcard and Computer.. Arch Intern Med. 1968;121(2):198-199. doi:10.1001/archinte.1968.03640020086028