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March 1968

Candida Endocarditis Surrounding a Starr-Edwards Prosthetic ValveRecovery of Candida in Hypertonic Medium During Treatment

Author Affiliations


From the Infectious Disease Division, Department of Medicine, University of Cincinnati College of Medicine, and the Cincinnati General Hospital.

Arch Intern Med. 1968;121(3):243-245. doi:10.1001/archinte.1968.03640030035005

Endocarditis caused by Candida parapsilosis surrounding the base of a Starr-Edwards prosthetic valve in a 40-year-old man is reported. During amphotericin B treatment, the infecting organism grew in hypertonic blood culture medium when there was no growth in ordinary blood cultures. At operation, bead-like friable, small vegetations were found instead of the large mass of vegetation commonly encountered in Candida endocarditis.