Endocarditis caused by Candida parapsilosis surrounding the base of a Starr-Edwards prosthetic valve in a 40-year-old man is reported. During amphotericin B treatment, the infecting organism grew in hypertonic blood culture medium when there was no growth in ordinary blood cultures. At operation, bead-like friable, small vegetations were found instead of the large mass of vegetation commonly encountered in Candida endocarditis.
Watanakunakorn C, Carleton J, Goldberg LM, Hamburger M. Candida Endocarditis Surrounding a Starr-Edwards Prosthetic ValveRecovery of Candida in Hypertonic Medium During Treatment. Arch Intern Med. 1968;121(3):243–245. doi:10.1001/archinte.1968.03640030035005